A dual-modal colorimetric and fluorescent probe based on 1,8-naphthalimide, 4-(2,2-dichloroacetamide)-N-n-butyl-naphthalimide (CNA), has been designed and synthesized for the detection of fluoride anion (F⁻) in CH₃CN. CNA exhibited highly sensitivity and selectivity for F⁻ over the other anions, such as Cl⁻, Br⁻, I⁻, NO₃⁻, ClO₄⁻, HSO₄⁻, NO₂⁻ and SCN⁻. The evident colorless to yellow color change of the solution of CNA was observed with the naked eyes only in the presence of F⁻ among the other anions, together with drastically fluorescence quenched. The Job's plot analysis revealed that the binding between the CNA with F⁻ was in 1:1 stoichiometry. The detection limits of the CNA for F⁻ from fluorescence and ratiometric absorption spectra were 0.52, 1.41 μM, respectively. The ¹H NMR titration indicated that F⁻ induced the deprotonation of the CNA through hydrogen bonding interaction between amino group of the CNA and F⁻. Based on this detection system, an IMPLICATION logic gate could be constructed. Furthermore, it could be successfully employed as a selective fluoride anion probe to the fluorescence detection of fluorine containing pesticides (oxyfluorfen).

基于1,8-萘二甲酰亚胺，4-（2,2-二氯乙酰胺）-NN丁基萘二甲酰亚胺（A双重峰比色和荧光探针CNA），已经设计并用于检测氟阴离子的合成（F ^- ）在CH ₃ CN中 CNA高度表现出的灵敏度和选择性与F ^-在其它阴离子，如Cl ^- ，溴^- ，我^-，NO ₃ ^-，CLO ₄ ^-，HSO ₄ ^-，NO ₂ ^-和SCN ^- 。CNA溶液明显无色至黄色的变化用裸眼观察只在F的存在^-所述其它阴离子中，连同急剧荧光淬灭。作业的情节分析表明之间的结合CNA使用F ^-在1：1层的化学计量。所述的检测限CNA与F ^-从荧光和比例吸收光谱分别为0.52，1.41μM，分别。的^1个1 H NMR滴定表明˚F ^-诱导的去质子化CNA通过氢键相互作用氨基之间CNA和F ^-。基于此检测系统，可以构建IMPLICATION逻辑门。此外，它可以成功地用作选择性氟阴离子探针，用于荧光检测含氟农药（oxyfluorfen）。