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Is it time to give up on “self-management” of COPD exacerbations?
European Respiratory Journal ( IF 24.3 ) Pub Date : 2020-01-01 , DOI: 10.1183/13993003.02102-2019
Sanjay Ramakrishnan 1 , Mona Bafadhel 2
Affiliation  

We read with interest the report of the results of the COPE-III trial by Lenferink et al. [1]. This large randomised trial continues on from the authors’ earlier COPE-II study [1], with personalised exacerbation action plans based on associated comorbidities. The action plans were detailed, and designed to determine symptom changes and the signs of an ensuing exacerbation. The study was negative for its primary endpoint (COPD exacerbation days) and no improvement in quality of life was found using the self-management intervention. COPD exacerbation self-management does not reduce COPD exacerbation days or hospitalisation, rather to more oral corticosteroid use and is rarely effective as it is not targeted http://bit.ly/33D89jF

中文翻译:

是时候放弃 COPD 急性加重的“自我管理”了吗?

我们饶有兴趣地阅读了 Lenferink 等人关于 COPE-III 试验结果的报告。[1]。这项大型随机试验延续了作者早期的 COPE-II 研究 [1],根据相关的合并症制定了个性化的恶化行动计划。行动计划很详细,旨在确定症状变化和随后恶化的迹象。该研究的主要终点(COPD 恶化天数)为阴性,使用自我管理干预未发现生活质量有所改善。COPD 急性加重的自我管理不会减少 COPD 急性加重的天数或住院,而是更多地使用口服皮质类固醇并且很少有效,因为它不是针对性的 http://bit.ly/33D89jF
更新日期:2020-01-01
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