The first large-scale vaccination campaign using needle-free jet injectors to administer fractional doses of inactivated poliovirus vaccine (fIPV) was conducted in Karachi, Pakistan, in February 2019. Data on acceptability of jet injectors were collected from 610 vaccinators and 4898 caregivers during the first four days of the campaign. Of those with prior needle and syringe experience, both vaccinators and caregivers expressed a strong preference for jet injectors (578/592 [97.6%] and 4792/4813 [99.6%], respectively), citing ease of use, appearance, and child's response to vaccination. Among caregivers, 4638 (94.7%) stated they would be more likely to bring their child for vaccination in a future campaign that used jet injectors. Mean vaccine coverage among towns administering fIPV was 98.7% - an increase by 18.4% over the preceding campaign involving full-dose IPV. Our findings demonstrate the strong acceptability of fIPV jet injectors and highlight the potential value of this method in future mass campaigns.

中文翻译：

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巴基斯坦卡拉奇市用于小剂量灭活脊髓灰质炎疫苗大规模给药的无针注射器：护理者和接种者可接受性的调查。

于2019年2月在巴基斯坦卡拉奇开展了首个大规模的疫苗接种运动，使用无针喷射注射器来施用部分剂量的灭活脊髓灰质炎病毒疫苗（fIPV）。广告活动的前四天。在那些以前有针头和注射器经验的人中，疫苗接种者和看护者均表示对喷射器的强烈偏好（分别为578/592 [97.6％]和4792/4813 [99.6％]），原因是易于使用，外观和儿童反应接种疫苗。在看护者中，有4638名（94.7％）表示，他们有可能在未来使用喷射器的运动中带孩子进行疫苗接种。使用fIPV的城镇平均疫苗覆盖率为98.7％，增加了18。较之前涉及全剂量IPV的广告系列高出4％。我们的发现证明了fIPV喷射注射器的强大接受性，并强调了这种方法在未来的大规模运动中的潜在价值。