Patulin is a toxic mycotoxin usually associated with apple products. Due to its unhealthy effects for humans, its content is regulated by the food safety authorities. The removal or degradation of this mycotoxin in contaminated apple juices has been studied with different approaches with uneven effectiveness. However, a strategy based on the chemical reaction between patulin and glutathione (GSH), in order to generate the conjugates that are formed during cell detoxification process, is an innovative approach yet to be evaluated. In this work, the formation of patulin-GSH conjugates activated by the application of pulsed light treatments and catalyzed by Fe2+ ions was evaluated. The study of patulin degradation and effect of the GSH/Fe2+ molar ratio showed that a molar ratio of 5 allows an adequate catalytic effect of the metal ions. In addition, mono-substituted patulin-glutathione adducts were identified as the main type of generated conjugates.

中文翻译：

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脉冲光诱导的棒曲霉素-谷胱甘肽缀合物的形成：苹果汁中棒曲霉素降解的尝试性策略。

棒曲霉素是一种有毒的霉菌毒素，通常与苹果产品有关。由于其对人类的不健康影响，其含量受食品安全当局的管制。已经用不同的方法研究了这种霉菌毒素在受污染的苹果汁中的去除或降解，但效果不一。然而，一种基于棒曲蛋白和谷胱甘肽（GSH）之间化学反应的策略，以生成在细胞排毒过程中形成的结合物，是一种尚待评估的创新方法。在这项工作中，评估了通过应用脉冲光处理激活并被Fe2 +离子催化的棒曲霉素-GSH共轭物的形成。对棒曲霉素降解和GSH / Fe2 +摩尔比的影响的研究表明，摩尔比为5可使金属离子具有足够的催化作用。此外，