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Simplicity in the Design, Operation, and Applications of Mechanically Interlocked Molecular Machines.
ACS Central Science ( IF 18.2 ) Pub Date : 2020-01-22 , DOI: 10.1021/acscentsci.9b01185
Andrew W Heard 1 , Stephen M Goldup 1
Affiliation  

Mechanically interlocked molecules are perhaps best known as components of molecular machines, a view further reinforced by the Nobel Prize in 2016 to Stoddart and Sauvage. Despite amazing progress since these pioneers of the field reported the first examples of molecular shuttles, genuine applications of interlocked molecular machines remain elusive, and many barriers remain to be overcome before such molecular devices make the transition from impressive prototypes on the laboratory bench to useful products. Here, we discuss simplicity as a design principle that could be applied in the development of the next generation of molecular machines with a view to moving toward real-world applications of these intriguing systems in the longer term.

中文翻译:

机械互锁分子机器的设计,操作和应用中的简单性。

机械互锁的分子也许是分子机器的组成部分,这一点在2016年诺贝尔奖获得者Stoddart和Sauvage的支持下得到了进一步证明。尽管自从这些领域的先驱者报道了分子穿梭机的第一个例子以来,取得了惊人的进步,但是联锁分子机器的真正应用仍然难以捉摸,在这种分子装置从实验室工作台上的令人印象深刻的原型过渡到有用的产品之前,仍有许多障碍需要克服。 。在这里,我们将简单性作为一种设计原则进行讨论,可以将其应用于下一代分子机器的开发中,以期从更长远的角度转向这些有趣系统的实际应用。
更新日期:2020-02-26
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