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Global burden of cancer attributable to infections: the critical role of implementation science.
The Lancet Global Health ( IF 34.3 ) Pub Date : 2020-02-01 , DOI: 10.1016/s2214-109x(20)30001-2
Anne F Rositch 1
Affiliation  

Despite significant advances in methodology and data quality since the first estimation of the global burden of cancer attributable to infections, one key fact remains: infections are responsible for at least a sixth of all cancer cases worldwide. In the latest set of estimates in this issue of The Lancet Global Health, Catherine de Martel and colleagues use newly released 2018 GLOBOCAN cancer incidence data to estimate for the first time age-standardised incidence rates of infection-attributable cancers at the country, regional, and global level. While many sources of uncertainty remain (including global variations in data completeness, quality of case detection and inclusion in cancer registries, and challenges in estimation of population denominators), incidence rates, as opposed to attributable fractions, provide policy makers with a more actionable metric of the burden of infection-associated cancers within and between populations over time. De Martel and colleagues report an astounding 25 cases of infection-attributable cancer per 100 000 people in 2018, with global variation ranging from 38 and 33 cases per 100 000 in eastern Asia and sub-Saharan Africa, respectively, to 14 cases per 100 000 in northern Europe and western Asia.

中文翻译:

感染引起的全球癌症负担:实施科学的关键作用。

尽管自从首次估算出可归因于感染的全球癌症负担以来,方法和数据质量已有了长足进步,但仍然存在一个关键事实:感染占全世界所有癌症病例的至少六分之一。,  ,  , 在这个问题上的最新的一组估计的柳叶刀全球健康,Catherine de Martel及其同事使用最新发布的2018 GLOBOCAN癌症发病率数据首次估算了国家,地区和全球范围内按年龄标准化的感染归因癌症的发病率。尽管仍然存在许多不确定性来源(包括数据完整性的全球差异,癌症检测中病例发现和纳入的质量以及人口分母的估计方面的挑战),但相对于可归因的分数,发病率为决策者提供了更具可行性的指标随着时间的推移,人群中和人群之间与感染相关的癌症负担的增加。De Martel及其同事报告称,2018年,每10万人中有25例感染引起的癌症病例令人震惊,全球变化在东亚和撒哈拉以南非洲地区每10万人中有38例至33例,
更新日期:2020-01-23
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