Chemical shift plays an important role in molecular analysis. However, chemical shifts are influenced by temperature, solvent concentration, pressure, etc. Therefore, measuring chemical shifts perturbations caused by these factors is helpful to molecular studies. A new form of two-dimensional spectroscopy (projection spectroscopy) has been introduced whose indirect dimension is derived by implementing the Radon transform on a series of conventional 1D proton spectra and indicates such perturbations. However, signal overlap may exist in the conventional 1D spectra and hence in the resulting projection spectra, hampering clear multiplet analysis and accurate extraction of perturbations. Here the pure shift decoupling technique is employed to obtain a cleaner and clearer projection spectrum with higher spectral resolution. The combination of pure shift technique and the Radon transform is helpful to accurately extract chemical shift perturbations. It is believed that this application will open up a vast prospect for molecular analysis.

中文翻译：

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基于氡变换和纯位移技术的高分辨率 2D NMR 光谱，用于研究化学位移扰动

化学位移在分子分析中起着重要作用。然而，化学位移受温度、溶剂浓度、压力等的影响。因此，测量由这些因素引起的化学位移扰动有助于分子研究。引入了一种新形式的二维光谱（投影光谱），其间接维数是通过对一系列传统的一维质子光谱实施氡变换得出的，并指示此类扰动。然而，信号重叠可能存在于传统的一维光谱中，因此在所得的投影光谱中可能存在，阻碍了清晰的多重分析和扰动的准确提取。这里采用纯移相去耦技术以获得更清晰、光谱分辨率更高的投影光谱。纯位移技术与Radon变换的结合有助于准确提取化学位移扰动。相信这一应用将为分子分析开辟广阔的前景。