Abstract Resistance is of great importance for controlling the current flow through bipolar electrodes (BPEs) and the electrochemiluminescence (ECL) signal at the BPE anode. In this work, we firstly studied the effect of the iR drop between the BPE cathode and anode on the electrochemical performance of a closed BPE device. Due to the significant iR loss between the two poles of the BPE, an increased external voltage, applied on the driving electrodes, was required to trigger the redox reactions at the BPE. Accordingly, the peak voltages (forward and reverse scan) shifted to larger values, whereas the current flow through the BPE was remarkably reduced. Moreover, these factors were closely dependent on the concentration of Fe(CN)63−/Fe(CN)64−, the scan rate, and the resistance wired between glassy carbon electrodes (GCEs). Principally, it was proven that the peak-to-peak separation was enlarged as the scan rate and the concentration of Fe(CN)63−/Fe(CN)64− increased, even when the resistance between the two BPE poles was zero, indicating that the ohmic effect of the electrochemical cell is significant. Excellent linear relationships could be observed between the peak voltages and the resistance, enabling the designation of novel biosensors by connecting sensing units with tunable resistance between the GCEs. The noncontact electrochemical measurement could therefore be promising in biosensing applications.

中文翻译：

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基于欧姆损耗机制的封闭式双极电化学生物传感器用于非接触测量

摘要 电阻对于控制流经双极电极 (BPE) 的电流和 BPE 阳极的电化学发光 (ECL) 信号非常重要。在这项工作中，我们首先研究了 BPE 阴极和阳极之间的 iR 降对封闭 BPE 装置的电化学性能的影响。由于 BPE 的两个极点之间的显着 iR 损失，需要施加在驱动电极上的增加的外部电压来触发 BPE 的氧化还原反应。因此，峰值电压（正向和反向扫描）转移到更大的值，而流过 BPE 的电流显着降低。此外，这些因素与 Fe(CN)63-/Fe(CN)64- 的浓度、扫描速率和玻璃碳电极 (GCE) 之间的电阻密切相关。原则上，结果表明，即使在两个 BPE 极点之间的电阻为零时，随着扫描速率和 Fe(CN)63-/Fe(CN)64- 浓度的增加，峰间分离也会扩大，表明电化学电池的欧姆效应是显着的。在峰值电压和电阻之间可以观察到极好的线性关系，通过在 GCE 之间连接具有可调电阻的传感单元来指定新型生物传感器。因此，非接触式电化学测量在生物传感应用中很有前景。在峰值电压和电阻之间可以观察到极好的线性关系，通过在 GCE 之间连接具有可调电阻的传感单元来指定新型生物传感器。因此，非接触式电化学测量在生物传感应用中很有前景。在峰值电压和电阻之间可以观察到极好的线性关系，通过在 GCE 之间连接具有可调电阻的传感单元来指定新型生物传感器。因此，非接触式电化学测量在生物传感应用中很有前景。