Chronic interstitial nephritis in agricultural communities (CINAC) is a progressive form of tubulointerstitial nephritis affecting agricultural workers in different parts of the world. Its underlying etiology is not known, although a study by Vervaet and coworkers in this issue of Kidney International provides strong evidence that CINAC is a lysosomal tubulopathy induced by toxin exposure. Key to this important discovery is a thorough morphologic analysis of kidney tissue, including ultrastructural as well as histopathologic examination.

中文翻译：

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揭露CINAC的病因，这是一个复杂而神秘的肾综合征：组织病理学和电子显微镜的重要作用。

农业社区慢性间质性肾炎（CINAC）是一种渐进性的肾小管间质性肾炎，影响世界各地的农业工人。尽管Vervaet及其同事在此期《国际肾脏病》杂志上进行的一项研究提供了有力的证据，表明CINAC是由毒素暴露引起的溶酶体微管病，但其潜在病因尚不清楚。这项重要发现的关键是对肾脏组织进行全面的形态分析，包括超微结构以及组织病理学检查。