Abstract Thermal hazards of reactive chemicals have been a major concern due to the unceasing occurrences of fire and explosion accidents in industry. Understanding thermal threats of these chemicals not only contributes to the process safety and sustainability in the research and development (RD whereby, the main limitations and challenges to be faced are explored. The discussed key points include, the classification and reactivity of typical reactive chemicals, the fundamental steps towards the comprehensive understanding of their thermal hazards (including the identification of reaction mechanisms, the calculation of reaction kinetics and thermodynamics, and the characterization of thermal safety properties), and the applicable theoretical, experimental and engineering approaches in each step. The primary goal of this review is to lay out the essential basics that should be focused in every trial to comprehensively understand the thermal hazards of reactive chemicals. The further research directions are also presented based on the current research gaps and the context of Industry 4.0.

中文翻译：

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工业中反应性化学品的热危害评估：最新技术和前景

摘要 由于工业中火灾和爆炸事故的不断发生，反应性化学品的热危害一直是人们关注的主要问题。了解这些化学品的热威胁不仅有助于研究和开发过程中的安全性和可持续性（研究，探索将面临的主要限制和挑战。讨论的关键点包括典型反应性化学品的分类和反应性，全面了解其热危害的基本步骤（包括反应机制的识别、反应动力学和热力学的计算以及热安全特性的表征），以及每个步骤中适用的理论、实验和工程方法。本综述的主要目标是列出每项试验中应重点关注的基本基础知识，以全面了解反应性化学品的热危害。还根据当前的研究空白和工业 4.0 的背景提出了进一步的研究方向。