By adding hyaluronic acid (HA) to dioctyl sodium sulfosuccinate (AOT)-stabilized gold nanotriangles (AuNTs) with an average thickness of 7.5±1 nm and an edge length of about 175±17 nm, the AOT bilayer is replaced by a polymeric HA-layer leading to biocompatible nanoplatelets. The subsequent reduction process of tetrachloroauric acid in the HA-shell surrounding the AuNTs leads to the formation of spherical gold nanoparticles on the platelet surface. With increasing tetrachloroauric acid concentration, the decoration with gold nanoparticles can be tuned. SAXS measurements reveal an increase of the platelet thickness up to around 14.5 nm, twice the initial value of bare AuNTs. HRTEM micrographs show welding phenomena between densely packed particles on the platelet surface, leading to a crumble formation while preserving the original crystal structure. Crumbles crystallized on top of the platelets enhance the Raman signal by a factor of around 20, and intensify the plasmon-driven dimerization of 4-nitrothiophenol (4-NTP) to 4,4'-dimercaptoazobenzene in a yield of up to 50 %. The resulting crumbled nanotriangles, with a biopolymer shell and the absorption maximum in the second window for in vivo imaging, are promising candidates for biomedical sensing.

中文翻译：

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具有碎屑顶部的金纳米三角形及其对催化和表面增强拉曼光谱的影响。

通过将透明质酸（HA）添加到磺基丁二酸二辛酯（AOT）稳定的金纳米三角形（AuNTs）中，平均厚度为7.5±1 nm，边缘长度约为175±17 nm，AOT双层被聚合物HA取代层形成生物相容性纳米血小板。随后在AuNT周围的HA壳中四氯金酸的还原过程导致在血小板表面上形成球形金纳米颗粒。随着四氯金酸浓度的增加，可以调节金纳米颗粒的装饰。SAXS测量显示血小板厚度增加到大约14.5 nm，是裸AuNTs初始值的两倍。HRTEM显微照片显示了血小板表面上密集堆积的颗粒之间的焊接现象，在保持原始晶体结构的同时导致碎屑形成。血小板顶部结晶的碎屑将拉曼信号增强了约20倍，并增强了由等离激元驱动的4-硝基硫酚（4-NTP）向4,4'-二巯基偶氮苯的二聚作用，产率最高可达50％。产生的碎裂的纳米三角形具有生物聚合物壳，并且在第二个窗口中具有最大的体内成像吸收率，是生物医学传感的有希望的候选者。