Small but mighty : Small, terminal alkynes were biosynthetically incorporated into α‐synuclein as vibrational reporters. These bio‐orthogonal probes are very powerful in providing site‐specific information on protein conformational changes in cells, such as protein–lipid interactions.

中文翻译：

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末端炔烃作为溶液和细胞中 α-突触核蛋白的拉曼探针。

小而强大：小末端炔烃作为振动报告基因通过生物合成并入 α-突触核蛋白。这些生物正交探针在提供细胞中蛋白质构象变化的位点特异性信息方面非常强大，例如蛋白质-脂质相互作用。