A direct and enantioselective oxidative cross-coupling of racemic 2,2-diarylacetonitriles with electron-rich (hetero)arenes has been described, which allows for efficient construction of triarylmethanes bearing all-carbon quaternary stereocenters with excellent chemo- and enantioselectivity. The reaction has an excellent functional group tolerance, and exhibits a broad scope with respect to both 2,2-diarylacetonitrile and (hetero)arene components. The rich chemistry of the cyano group allows for facile synthesis of other valuable chiral triarylmethanes bearing all-carbon quaternary centers that are otherwise difficult to access.

中文翻译：

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带有全碳四元立体中心的手性三芳基甲烷的合成：2,2-二芳基乙腈和（杂）芳烃的催化不对称氧化交叉偶联。

已经描述了外消旋2，2-二芳基乙腈与富含电子的（杂）芳烃的直接和对映选择性的氧化交叉偶联，其允许具有优异的化学和对映选择性的有效构建带有全碳四元立体中心的三芳基甲烷。该反应具有优异的官能团耐受性，并且对于2，2-二芳基乙腈和（杂）芳烃组分均显示出宽范围。氰基的化学性质丰富，可以轻松合成带有全碳季中心的其他有价值的手性三芳基甲烷。