A 28-year-old male presented with complaints of heartburn and reflux, diagnosed as Gastroesophageal reflux disease (GERD) with Proton Pump Inhibitor (PPI) dependence. On 24-hpH metry, DeMeester Score was 168 and fraction of time at pH < 4 of 26%. Endoscopy revealed laxity of lower esophageal sphincter, endoscopic Hill grade II and small hiatal hernia. Patient had symptoms (> 2 years) despite optimal therapy. Post consent, he underwent successful Endoscopic full thickness plication with GERDxTM device (G-SURG, Germany) (Fig-a). Procedure was uneventful hence discharged on second day.

中文翻译：

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一名 28 岁亚洲男性内镜下全层褶皱术后贫血的不寻常原因

一名 28 岁男性主诉胃灼热和反流，被诊断为胃食管反流病 (GERD) 伴质子泵抑制剂 (PPI) 依赖。在 24-hpH 测量中，DeMeester 得分为 168，pH < 4 的时间分数为 26%。内镜检查显示食管下括约肌松弛，内镜下希尔Ⅱ级和小裂孔疝。尽管接受了最佳治疗，患者仍有症状（> 2 年）。同意后，他使用 GERDxTM 设备（G-SURG，德国）成功接受了内窥镜全层折叠术（图 a）。手术很顺利，第二天就出院了。