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Invertebrates facing environmental contamination by endocrine disruptors: Novel evidences and recent insights.
Molecular and Cellular Endocrinology ( IF 4.1 ) Pub Date : 2020-01-18 , DOI: 10.1016/j.mce.2020.110712 Virginie Cuvillier-Hot 1 , Alain Lenoir 2
Molecular and Cellular Endocrinology ( IF 4.1 ) Pub Date : 2020-01-18 , DOI: 10.1016/j.mce.2020.110712 Virginie Cuvillier-Hot 1 , Alain Lenoir 2
Affiliation
The crisis of biodiversity we currently experience raises the question of the impact of anthropogenic chemicals on wild life health. Endocrine disruptors are notably incriminated because of their possible effects on development and reproduction, including at very low doses. As commonly recorded in the field, the burden they impose on wild species also concerns invertebrates, with possible specificities linked with the specific physiology of these animals. A better understanding of chemically-mediated endocrine disruption in these species has clearly gained from knowledge accumulated on vertebrate models. But the molecular pathways specific to invertebrates also need to be reckoned, which implies dedicated research efforts to decipher their basic functioning in order to be able to assess its possible disruption. The recent rising of omics technologies opens the way to an intensification of these efforts on both aspects, even in species almost uninvestigated so far.
中文翻译:
面临内分泌干扰物污染的无脊椎动物:新证据和最新见解。
我们目前经历的生物多样性危机提出了人为化学物质对野生生物健康的影响的问题。内分泌干扰物特别明显,因为它们可能对发育和生殖产生影响,包括低剂量时。正如在该领域中普遍记录的那样,它们对野生物种造成的负担也涉及无脊椎动物,其可能的特异性与这些动物的特定生理状况有关。从脊椎动物模型上积累的知识显然可以更好地了解这些物种中的化学介导的内分泌破坏。但是,无脊椎动物特有的分子途径也需要考虑,这意味着需要专门的研究工作来解释其基本功能,以便能够评估其可能的破坏。
更新日期:2020-01-21
中文翻译:
面临内分泌干扰物污染的无脊椎动物:新证据和最新见解。
我们目前经历的生物多样性危机提出了人为化学物质对野生生物健康的影响的问题。内分泌干扰物特别明显,因为它们可能对发育和生殖产生影响,包括低剂量时。正如在该领域中普遍记录的那样,它们对野生物种造成的负担也涉及无脊椎动物,其可能的特异性与这些动物的特定生理状况有关。从脊椎动物模型上积累的知识显然可以更好地了解这些物种中的化学介导的内分泌破坏。但是,无脊椎动物特有的分子途径也需要考虑,这意味着需要专门的研究工作来解释其基本功能,以便能够评估其可能的破坏。