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Comment on Liu et al. Aberrant Expression of FBXO2 Disrupts Glucose Homeostasis Through Ubiquitin-Mediated Degradation of Insulin Receptor in Obese Mice. Diabetes 2017;66:689–698
Diabetes ( IF 7.7 ) Pub Date : 2020-01-20 , DOI: 10.2337/db19-0975
Siauyen Wong 1 , Rick F Nelson 2 , Peiran Lu 1 , Henry Paulson 3 , Dingbo Lin 4
Affiliation  

We appreciate Wong et al. (1) for their interest in our article (2). The specificity of an antibody could be affected by many factors including the detergents, blocking reagent, and incubating time and temperature as well as the quantity of secondary antibody. Wong et al. claimed that F-box only protein 2 (FBXO2) might not mediate glucose homeostasis in …

中文翻译:

评论刘等人。FBXO2 的异常表达通过泛素介导的胰岛素受体降解破坏了肥胖小鼠的葡萄糖稳态。糖尿病 2017;66:689–698

我们感谢 Wong 等人。(1) 因为他们对我们的文章 (2) 感兴趣。抗体的特异性可能受许多因素影响,包括去污剂、封闭剂、孵育时间和温度以及二抗的数量。王等人。声称 F-box only protein 2 (FBXO2) 可能不会介导葡萄糖稳态……
更新日期:2020-01-20
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