As reported in Chemosphere by Colles et al. (2020), there are multiple pathways for human exposure to poly- and perfluoroalkyl substances (PFAS). Now, a new chemical formation of C-F bonds in drug delivery lead to concerns for human exposure as these inert chemical formations are resistance to metabolic degradation and excretion.

中文翻译：

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在药物输送中要谨慎使用碳氟键。

如Colles等人在Chemosphere中报道的。（2020），人类接触多氟烷基和全氟烷基物质（PFAS）的途径多种多样。现在，药物递送中CF键的新化学形成引起人们的关注，因为这些惰性化学形成对代谢降解和排泄具有抵抗力。