Functional near-infrared spectroscopy (fNIRS), an imaging tool that utilizes infrared light to measure changes within the concentration of oxygenated (HbO) and deoxygenated (HbR) hemoglobin, holds promise to study functional activity from motor, visual, and memory cortical regions using stimulus-induced tasks. This study investigated the reliability for fNIRS to examine cortical activations within the frontal eye fields (FEF) while initiating vergence eye movements, the inward and outward rotation of the eyes. FNIRS data were collected from twenty participants with normal binocular vision while performing vergence eye movements compared to sustained gaze fixation within a block design during two different sessions. Reliability of the experimental protocol was assessed using the intraclass correlation coefficient (ICC). The ICC values ranged from 0.6 to 0.7 for measuring the HbO activation within the vicinity of the FEF. A frequency power spectrum analysis revealed two predominant frequencies within the functional activation signals from the FEF. One high-intensity signal was present at 0.029 Hz, centering around the block design frequency. The peak-intensity signal was observed between 0.012 and 0.018 Hz where this very low-frequency oscillation (VLFO) was hypothesized to be generated by the macrovasculature present near the FEF and should be avoided as a block design frequency in future fNIRS studies to avoid false positive results.

中文翻译：

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散光眼动过程中观察到的前眼视野激活和非常低频振荡的可靠性：fNIRS研究。

功能性近红外光谱（fNIRS）是一种利用红外光测量氧化性（HbO）和脱氧性（HbR）血红蛋白浓度范围内变化的成像工具，它有望利用以下方法研究运动，视觉和记忆皮层区域的功能活动：刺激性任务。这项研究调查了fNIRS在开始发散眼球运动，眼睛向内和向外旋转时检查额叶视野（FEF）内皮质激活的可靠性。FNIRS数据是从二十名具有正常双眼视力的参与者收集的，同时进行了散瞳眼动运动，而在两个不同的阶段中，在块体设计中持续注视固定。使用组内相关系数（ICC）评估实验方案的可靠性。ICC值的范围是0。图6至0.7用于测量FEF附近的HbO活化。频谱分析表明，FEF的功能激活信号中有两个主要频率。以模块设计频率为中心，出现了一个高强度信号，频率为0.029 Hz。观测到的峰值强度信号在0.012至0.018 Hz之间，其中该低频振荡（VLFO）可能是由FEF附近的大脉管系统产生的，在以后的fNIRS研究中应避免将其作为模块设计频率，以避免错误积极的结果。以模块设计频率为中心。观测到的峰值强度信号在0.012至0.018 Hz之间，其中该低频振荡（VLFO）可能是由FEF附近的大脉管系统产生的，在以后的fNIRS研究中应避免将其作为模块设计频率，以避免错误积极的结果。以模块设计频率为中心。观测到的峰值强度信号在0.012至0.018 Hz之间，其中该低频振荡（VLFO）可能是由FEF附近的大脉管系统产生的，在以后的fNIRS研究中应避免将其作为模块设计频率，以避免错误积极的结果。