Multifunctional nanoparticulate systems, especially those used in medicine, are currently of great interest. In this work, the in-vitro anticancer activity of As₄S₄/Fe₃O₄ composites dispersed in a water solution of Poloxamer 407 on breast MCF-7 and tongue SCC-25 cancer cells was verified. An increase in apoptotic cells as a consequence of higher caspase activities, a decrease in mitochondrial membrane potential and an accumulation of cells in the G2/M and subG0/G1 phases were detected after treatment with the As₄S₄/Fe₃O₄ nanosuspensions. The sterically stabilized nanosuspensions were characterized in relation to their particle size distribution, zeta potential and long-term stability properties. The interaction between the solid and liquid phases of the nanosuspensions was also studied using Fourier transform infrared spectroscopy.

多功能纳米颗粒系统，特别是用于医学的纳米颗粒系统，目前引起人们极大的兴趣。在这项工作中，验证了分散在泊洛沙姆407水溶液中的As ₄ S ₄ / Fe ₃ O ₄复合物对乳腺癌MCF-7和舌状SCC-25癌细胞的体外抗癌活性。As ₄ S ₄ / Fe ₃ O ₄处理后，由于半胱天冬酶活性较高，凋亡的线粒体膜电位降低以及G2 / M和subG0 / G1期细胞堆积而导致凋亡细胞增加。纳米悬浮液。相对于它们的粒度分布，ζ电势和长期稳定性，对空间稳定的纳米悬浮液进行了表征。还使用傅里叶变换红外光谱法研究了纳米悬浮液的固相和液相之间的相互作用。