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The characterisation of subjective cognitive decline
The Lancet Neurology ( IF 48.0 ) Pub Date : 2020-03-01 , DOI: 10.1016/s1474-4422(19)30368-0
Frank Jessen 1 , Rebecca E Amariglio 2 , Rachel F Buckley 3 , Wiesje M van der Flier 4 , Ying Han 5 , José Luis Molinuevo 6 , Laura Rabin 7 , Dorene M Rentz 2 , Octavio Rodriguez-Gomez 8 , Andrew J Saykin 9 , Sietske A M Sikkes 10 , Colette M Smart 11 , Steffen Wolfsgruber 12 , Michael Wagner 13
Affiliation  

A growing awareness about brain health and Alzheimer's disease in the general population is leading to an increasing number of cognitively unimpaired individuals, who are concerned that they have reduced cognitive function, to approach the medical system for help. The term subjective cognitive decline (SCD) was conceived in 2014 to describe this condition. Epidemiological data provide evidence that the risk for mild cognitive impairment and dementia is increased in individuals with SCD. However, the majority of individuals with SCD will not show progressive cognitive decline. An individually tailored diagnostic process might be reasonable to identify or exclude underlying medical conditions in an individual with SCD who actively seeks medical help. An increasing number of studies are investigating the link between SCD and the very early stages of Alzheimer's disease and other neurodegenerative diseases.

中文翻译:

主观认知衰退的表征

普通人群对大脑健康和阿尔茨海默病的认识不断提高,导致越来越多的认知功能正常的人担心自己的认知功能下降,向医疗系统寻求帮助。主观认知能力下降 (SCD) 一词是在 2014 年构思的,用于描述这种情况。流行病学数据提供的证据表明,SCD 患者发生轻度认知障碍和痴呆的风险增加。然而,大多数 SCD 患者不会表现出进行性认知能力下降。单独定制的诊断过程可能是合理的,可以识别或排除积极寻求医疗帮助的 SCD 患者的潜在医疗状况。
更新日期:2020-03-01
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