当前位置: X-MOL 学术Clin. Neurophysiol. › 论文详情
Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)
Delayed neonatal visual evoked potentials are associated to asymmetric growth pattern in twins
Clinical Neurophysiology ( IF 4.7 ) Pub Date : 2020-03-01 , DOI: 10.1016/j.clinph.2019.12.407
Ettore Piro 1 , Agnese Suppiej 2 , Giuseppe Puccio 1 , Raffaele Falsaperla 3 , Giovanni Corsello 1
Affiliation  

OBJECTIVES To study the association between intrauterine growth and visual pathways maturation by neonatal visual evoked potentials (VEPs) in twins, in view of a possible prognostic role. METHODS Seventy-four twin neonates from 37 pregnancies were selected based on gestational age of more than 30 weeks and uneventful perinatal clinical course. Flash VEPs were recorded at the same postmenstrual age in each twin pair. The association between P2 latency and anthropometric variables at birth was analyzed by comparison within each twin pair and regarding each variable as ordered difference between the two twins. RESULTS Analysis of differences within each twin pair highlighted that inter-twin difference in P2 latency was significantly related to difference in ponderal index (PI) (p = 0.048). Expressing the difference in latency as a categorical binary variable, the correlation was significant for both difference in PI, (median difference = -0.36, 95% CI -0.54 to -0.14, p = 0.001) and difference in body mass index (BMI), (median difference = -1.06, 95% CI -1.74 to -0.29, p = 0.006). CONCLUSIONS Lower values of PI and BMI differences are associated to delayed VEP latency in twin pairs. SIGNIFICANCE VEP latency suggests reduced myelination of visual pathways when difference in growth pattern occurs in twins.

中文翻译:

延迟的新生儿视觉诱发电位与双胞胎的不对称生长模式有关

目的 考虑到可能的预后作用,研究双胞胎新生儿视觉诱发电位 (VEP) 的宫内生长与视觉通路成熟之间的关联。方法根据胎龄大于30周,围产期临床病程顺利,从37例妊娠中筛选出74例双胎新生儿。在每对双胞胎中,在相同的经后年龄记录了 Flash VEP。通过在每对双胞胎内进行比较并将每个变量视为两个双胞胎之间的有序差异,分析了 P2 潜伏期与出生时人体测量变量之间的关联。结果 每对双胞胎内的差异分析强调,双胞胎间 P2 潜伏期的差异与重量指数 (PI) 的差异显着相关 (p = 0.048)。将延迟差异表示为分类二元变量,相关性对于 PI 差异(中值差异 = -0.36,95% CI -0.54 至 -0.14,p = 0.001)和体重指数 (BMI) 差异均显着,(中位数差 = -1.06,95% CI -1.74 至 -0.29,p = 0.006)。结论 较低的 PI 和 BMI 差异值与双胞胎中延迟的 VEP 潜伏期有关。意义 VEP 潜伏期表明当双胞胎的生长模式存在差异时,视觉通路的髓鞘形成减少。结论 较低的 PI 和 BMI 差异值与双胞胎中延迟的 VEP 潜伏期有关。意义 VEP 潜伏期表明当双胞胎的生长模式存在差异时,视觉通路的髓鞘形成减少。结论 PI 和 BMI 差异的较低值与双胞胎中延迟的 VEP 潜伏期相关。意义 VEP 潜伏期表明当双胞胎的生长模式存在差异时,视觉通路的髓鞘形成减少。
更新日期:2020-03-01
down
wechat
bug