Clinical Oral Investigations ( IF 3.4 ) Pub Date : 2020-01-16 , DOI: 10.1007/s00784-019-03148-9 I Laleman 1 , C Dekeyser 1 , A Wylleman 1 , W Teughels 1 , M Quirynen 1
Objectives
Already decades ago, the diagnosis of halitosis was facilitated with the arrival of chair-side instruments to score the breath odor. These devices are used for a more objective assessment of halitosis compared with organoleptic scoring, but these too have their disadvantages. To overcome some of the drawbacks of the original model of the OralChromaTM (CHM-1), few years ago a second generation of this machine (CHM-2) was introduced. This study compared both devices in a clinical setting.
Materials and methods
All records of the patients visiting a specialized halitosis consultation over a period of 5 years (2012–2017) were examined. The correlations of the OralChromaTM CHM-1 and CHM-2 with the organoleptic and Halimeter® measurements were analyzed. Additionally the sensitivity, specificity, and negative and positive predicted values were calculated.
Results
A total of 581 data points were included (CHM-1: 292, CHM-2: 289). The correlations between both models with the organoleptic measurements were not statistically significant different. The CHM-2 seemed superior to the CHM-1 in the quantification of dimethyl sulfide with a detection rate of 95% and 61%, respectively. Additionally, the CHM-2 was significantly more sensitive for dimethyl sulfide than the CHM-1. However the latter showed in turn a better sensitivity for hydrogen sulfide and methyl mercaptan.
Conclusion
The CHM-2 showed a better sensitivity for dimethyl sulfide than its predecessor. However, its sensitivity for hydrogen sulfide and methyl mercaptan was worse.
Clinical relevance
Dimethyl sulfide is the main volatile implicated in extra-oral blood-borne halitosis, this makes the OralChromaTM CHM-2 the instrument of choice when this is suspected.
中文翻译:
OralChromaTM CHM-2:与OralChromaTM CHM-1的比较。
目标
早在数十年前,随着椅子旁仪器的出现,就为口臭的诊断提供了便利。与感官评分相比,这些设备可用于更客观地评估口臭,但它们也有其缺点。为了克服OralChroma TM(CHM-1)原始模型的某些缺点,几年前,该机的第二代产品(CHM-2)推出了。这项研究在临床环境中比较了这两种设备。
材料和方法
检查了过去5年(2012年至2017年)就诊的口臭专家的所有记录。分析了OralChroma TM CHM-1和CHM-2与感官和Halimeter®测量值的相关性。另外,还计算了敏感性,特异性以及阴性和阳性预测值。
结果
总共包括581个数据点(CHM-1:292,CHM-2:289)。两种模型与感官测量之间的相关性在统计学上没有显着差异。CHM-2在二甲基硫醚的定量分析中似乎优于CHM-1,检出率分别为95%和61%。另外,CHM-2对二甲基硫的敏感性比CHM-1高得多。然而,后者又显示出对硫化氢和甲硫醇的更好的敏感性。
结论
CHM-2对二甲基硫的敏感性比其前身更好。但是,它对硫化氢和甲硫醇的敏感性较差。
临床相关性
二甲基硫醚是与口腔外血源性口臭有关的主要挥发性物质,这使OralChroma TM CHM-2成为可疑的首选仪器。