Thiolated β-cyclodextrin functionalized gold nanoparticles (Au-β-CDs) with layered wrinkled flower structure were prepared. Au-β-CDs were electrostatically combined with protonated aminated graphene quantum dots (NH 2 -GQDs) to form a nanocomposite with better supramolecular recognition, conductivity, catalysis and dispersion properties. For constructing a quercetin (QU) sensor, the nanocomposites were one-step electrodeposited by a cyclic voltammetry (CV) method onto a glassy carbon electrode to form a stable film. Under optimized conditions, the sensor showed a wide linear response range of 1–210 nM, with a lower detection limit of 285 pM. At the same time, flavonoids with similar structures hardly interfere with the determination of QU. The sensor has been used to determine QU in honey, tea, honeysuckle and human serum with satisfactory results. Graphical abstract Schematic representation of the fabrication of an ultrasensitive quercetin electrochemical sensor based on aminated graphene quantum dots, thiolated β-cyclodextrin and gold nanoparticles (NH 2 -GQDs/Au-β-CD/GCE).

中文翻译：

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使用由胺化石墨烯量子点、硫醇化 β-环糊精和金纳米颗粒制备的纳米复合材料修饰的玻碳电极对槲皮素进行超灵敏电流法测定

制备了具有分层皱纹花结构的硫醇化β-环糊精功能化金纳米粒子（Au-β-CDs）。Au-β-CDs 与质子化胺化石墨烯量子点（NH 2 -GQDs）静电结合，形成具有更好的超分子识别、导电、催化和分散性能的纳米复合材料。为了构建槲皮素 (QU) 传感器，纳米复合材料通过循环伏安法 (CV) 方法一步电沉积到玻璃碳电极上以形成稳定的薄膜。在优化条件下，传感器显示出 1-210 nM 的宽线性响应范围，检测下限为 285 pM。同时，结构相似的黄酮类化合物几乎不会干扰QU的测定。该传感器已用于测定蜂蜜、茶叶、金银花和人血清中的QU，结果令人满意。