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The challenge of an expanded therapeutic window in pulmonary hypertension.
Nature Reviews Cardiology ( IF 49.6 ) Pub Date : 2020-01-16 , DOI: 10.1038/s41569-020-0332-9
Simon Stewart 1, 2 , Geoffrey A Strange 3 , David Playford 3
Affiliation  

Our understanding of the causes and consequences of pulmonary hypertension is limited. Consequently, its most distinctive forms with the worst prognosis have been the focus for diagnosis and treatment. We highlight the emerging challenge of reframing the prevalence and prognostic implications of pulmonary hypertension, focusing on the optimal therapeutic window to address the high mortality linked to this condition.

中文翻译:

在肺动脉高压中扩大治疗范围的挑战。

我们对肺动脉高压的原因和后果的了解是有限的。因此,其具有最差预后的最独特形式一直是诊断和治疗的重点。我们重点介绍了重新确定肺动脉高压的患病率和预后意义的新挑战,重点是解决与该病相关的高死亡率的最佳治疗窗口。
更新日期:2020-01-17
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