当前位置: X-MOL 学术Bioinformatics › 论文详情
Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)
Visualization of circular RNAs and their internal splicing events from transcriptomic data.
Bioinformatics ( IF 5.8 ) Pub Date : 2020-05-01 , DOI: 10.1093/bioinformatics/btaa033
Yi Zheng 1 , Fangqing Zhao 1, 2
Affiliation  

SUMMARY Circular RNAs (circRNAs) are proved to have unique compositions and splicing events distinct from canonical mRNAs. However, there is no visualization tool designed for the exploration of complex splicing patterns in circRNA transcriptomes. Here, we present CIRI-vis, a Java command-line tool for quantifying and visualizing circRNAs by integrating the alignments and junctions of circular transcripts. CIRI-vis can be applied to visualize the internal structure and isoform abundance of circRNAs and perform circRNA transcriptome comparison across multiple samples. AVAILABILITY AND IMPLEMENTATION https://sourceforge.net/projects/ciri/files/CIRI-vis. SUPPLEMENTARY INFORMATION Supplementary data are available at Bioinformatics online.

中文翻译:

从转录组数据可视化环状RNA及其内部剪接事件。

概述环状RNA(circRNA)被证明具有不同于典型mRNA的独特组成和剪接事件。但是,没有设计用于探索circRNA转录组中复杂剪接模式的可视化工具。在这里,我们介绍CIRI-vis,这是一个Java命令行工具,用于通过整合环形转录本的比对和连接来量化和可视化circRNA。CIRI-vis可用于可视化circRNA的内部结构和同工型丰度,并在多个样品之间进行circRNA转录组比较。可用性和实现https://sourceforge.net/projects/ciri/files/CIRI-vis。补充信息补充数据可从Bioinformatics在线获得。
更新日期:2020-01-17
down
wechat
bug