Dr. Gnanasekaran et al. reported the bactericidal activity of various concentrations of povidone iodine (PI) solution in an agar plate experiment of respiratory flora. The study design and the pharmacokinetic properties of PI solution ensured that dilute PI would not be effective in this study. These results may not replicate the typical clinical situation and are significantly different than a previously reported agar plate experiment, again owing to subtle but very significant differences in methodology.

中文翻译：

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聚维酮碘的药代动力学和研究设计。

Gnanasekaran博士等。报道了不同浓度的聚维酮碘溶液在呼吸道琼脂平板实验中的杀菌活性。PI溶液的研究设计和药代动力学特性确保了稀释的PI在该研究中无效。这些结果可能无法复制典型的临床情况，并且与先前报道的琼脂平板实验存在显着差异，同样是由于方法上的细微但非常显着的差异。