The complex between protoporphyrin IX and zinc was immobilized on nanocarbon paste and on nanodiamond paste to design two stochastic microsensors. The microsensors were used for the recognition and analysis of antibiotics: amoxicillin, ampicillin, and biotin in water samples. Stochastic sensors provided different signatures for the three antibiotics making possible their simultaneous recognition and assay in water samples. Low limits of determination 0.3 pg/mL for amoxicillin and ampicillin, and 0.21 pg/mL for biotin were obtained when nanocarbon paste was used, and 0.03 pg/mL for amoxicillin, 0.30 pg/mL for ampicillin, and 2.14 fg/mL for biotin were obtained when nanodiamond paste was used. Recoveries higher than 99.32 % with RSD lower than 1.00 % were obtained for the assay of the antibiotics in water samples.

中文翻译：

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原卟啉IX锌复合物修饰的纳米碳材料，水样品中公认的抗生素

原卟啉IX和锌之间的复合物被固定在纳米碳糊和纳米金刚石糊上，以设计两个随机微传感器。微型传感器用于识别和分析水样中的抗生素：阿莫西林，氨苄青霉素和生物素。随机传感器为三种抗生素提供了不同的特征，这使得它们在水样中的同时识别和测定成为可能。当使用纳米碳糊剂时，阿莫西林和氨苄青霉素的测定下限为0.3 pg / mL，生物素为0.21 pg / mL，阿莫西林为0.03 pg / mL，氨苄青霉素为0.30 pg / mL，生物素为2.14 fg / mL当使用纳米金刚石糊剂时获得。测定水样中的抗生素时，回收率高于99.32％，RSD低于1.00％。