当前位置: X-MOL 学术Bioconjugate Chem. › 论文详情
Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)
Covalently Conjugated Hydrogelators for Imaging and Therapeutic Applications.
Bioconjugate Chemistry ( IF 4.7 ) Pub Date : 2020-01-24 , DOI: 10.1021/acs.bioconjchem.9b00867
Xiaotong Cheng 1 , Jiaoming Jiang 1 , Gaolin Liang 1
Affiliation  

In recent years, research on supramolecular hydrogels for biomedical applications developed rapidly by covalently conjugating their hydrogelators with functional moieties including therapeutic agents and imaging probes. Such conjugation can not only endow hydrogels with specific functions but also enhance the performance of the functional moieties. Therefore, these evolutionary conjugates may create a great leap for the application of supramolecular hydrogels in clinical scenarios, especially in a bioimaging or a sustained drug release system. In order to draw inspiration from the rapid advancement in this field and establish cornerstones for innovative exploration in the follow-up research, herein, we review the recent advances of the covalently conjugated hydrogelators and their biomedical applications in imaging and therapies. Besides, we provide our views on the remaining challenges and a perspective on future trends of conjugated hydrogelators.

中文翻译:

用于成像和治疗应用的共价共轭水凝胶剂。

近年来,用于生物医学的超分子水凝胶的研究通过将其水凝胶剂与包括治疗剂和成像探针在内的功能性部分共价缀合而迅速发展。这种缀合不仅可以赋予水凝胶特定的功能,而且还可以增强功能部分的性能。因此,这些进化偶联物可能为超分子水凝胶在临床应用中,特别是在生物成像或持续药物释放系统中的应用创造巨大的飞跃。为了从该领域的快速发展中汲取灵感并为后续研究中的创新探索奠定基石,在这里,我们回顾了共价共轭水凝胶剂的最新进展及其在成像和治疗中的生物医学应用。除了,
更新日期:2020-01-26
down
wechat
bug