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Reply to Yates and Barr
Clinical Infectious Diseases ( IF 9.055 ) Pub Date : 2019-05-24 , DOI: 10.1093/cid/ciz434
Ugarte-Gil C, Pearson F, Moore D, et al.

To the Editor—We thank Drs Yates and Barr for their valuable comments. In our article [1], we were not attempting to assess the extent to which dysglycemia is causally associated with tuberculosis (TB). A number of prospective studies exist, among a body of evidence, supporting probabilistic causation between diabetes mellitus (DM) and TB [2, 3]. Rather, the aim of our study was to identify age-adjusted prevalence and clinical characteristics of DM and intermediate hyperglycemia among those with newly diagnosed TB across 4 TB-endemic settings. In our South African population, the prevalence of DM (10.9% [95% confidence interval, 7%–14.9%]) was the lowest across all 4 study sites. However, as the smallest site, uncertainty around this estimate is greatest and the prevalence estimate was shown to increase after age standardization.
更新日期:2020-01-16

 

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