当前位置: X-MOL 学术J. Org. Chem. › 论文详情
Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)
Ac2O-Mediated Dearylacetylative Dimerization of 2-Arylacetyl-1-naphthols: Synthesis of Naphtho[1,2-b]furan-3-ones.
The Journal of Organic Chemistry ( IF 3.6 ) Pub Date : 2020-01-24 , DOI: 10.1021/acs.joc.9b03298
Meng-Yang Chang,Kuan-Ting Chen,Yu-Ting Hsiao,Shin-Mei Chen

A novel and efficient route for the synthesis of 2-aryl-2-naphthyl naphtho[1,2-b]furan-3-ones is described via NaH/Ac2O-mediated dearylacetylative dimerization of 2-arylacetyl-1-naphthols in refluxing THF under open-flask conditions. A plausible mechanism is also proposed and discussed. Various reaction conditions are investigated for one-pot transformation.

中文翻译:

Ac 2 O介导的2-芳基乙酰基-1-萘的脱芳基乙酰化二聚反应:萘并[1,2-b]呋喃-3-酮的合成。

通过回流的THF中NaH / Ac2O介导的2-芳基乙酰基-1-萘的脱芳基乙酰化二聚作用,描述了一种合成2-芳基-2-萘基萘并[1,2-b]呋喃-3-酮的新颖有效途径。在开瓶条件下。还提出并讨论了一种可行的机制。一锅转化研究了各种反应条件。
更新日期:2020-01-24
down
wechat
bug