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Generation of an induced pluripotent stem cell line SYSUi-003-A from a child with epilepsy carrying GRIN2A mutation.
Stem Cell Research ( IF 1.2 ) Pub Date : 2020-01-15 , DOI: 10.1016/j.scr.2020.101706 Chuanbo Sun 1 , Mingzhu Yang 2 , Fengying Qin 3 , Ruirui Guo 2 , Shiqi Liang 2 , Hao Hu 4
中文翻译：
从携带GRIN2A突变的癫痫患儿中产生诱导性多能干细胞系SYSUi-003-A。
更新日期：2020-01-15
Stem Cell Research ( IF 1.2 ) Pub Date : 2020-01-15 , DOI: 10.1016/j.scr.2020.101706 Chuanbo Sun 1 , Mingzhu Yang 2 , Fengying Qin 3 , Ruirui Guo 2 , Shiqi Liang 2 , Hao Hu 4
Affiliation
We generated iPSCs from peripheral blood mononuclear cells of a child with epilepsy carrying heterozygous missense mutation in GRIN2A, using integration free episomal vectors. These iPSCs express pluripotent markers, represent a normal karyotype and have the ability to differentiate into three germ layers.
中文翻译：
从携带GRIN2A突变的癫痫患儿中产生诱导性多能干细胞系SYSUi-003-A。
我们使用无整合型游离载体从患有GRIN2A杂合错义突变的癫痫患儿的外周血单个核细胞中生成了iPSC 。这些iPSC表达多能标记，代表正常的核型，并具有分化为三个胚层的能力。
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