Benchtop nuclear magnetic resonance (NMR) spectroscopy is a useful tool for the rapid determination of the self‐diffusion coefficient and the hydrodynamic radius of dendrons. The self‐diffusion coefficients of the first four generations of poly ethoxy ethyl glycinamide (PEE‐G) dendrons are measured by diffusion‐ordered spectroscopy (DOSY) on a benchtop NMR equipped with diffusion gradient coils. The hydrodynamic radii of the dendrons are calculated via the Stokes–Einstein equation. The effects of solvent and pH are determined with the hydrodynamic radius increasing with generation and decreasing upon neutralization of an acidic solution. These measurements provide valuable information for biological and pharmaceutical applications of dendrons.

中文翻译：

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在台式 NMR 光谱仪上通过扩散光谱法测量 PEE-G 树枝状体的流体动力学半径

台式核磁共振（NMR）光谱是快速测定树突自扩散系数和流体动力学半径的有用工具。前四代聚乙氧基乙基甘氨酰胺（PEE-G）树突的自扩散系数通过扩散有序光谱法（DOSY）在配备有扩散梯度线圈的台式核磁共振仪上进行测量。树突的流体动力学半径通过斯托克斯-爱因斯坦方程计算。溶剂和 pH 值的影响取决于流体动力学半径随着酸性溶液的产生而增加和减少。这些测量为树突的生物和药物应用提供了有价值的信息。