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In situ analysis of oxytetracycline tablets based on matrix‐assisted laser desorption/ionization mass spectrometry imaging
Rapid Communications in Mass Spectrometry ( IF 2 ) Pub Date : 2020-01-15 , DOI: 10.1002/rcm.8592
Hanyi Xie 1 , Qichuan He 1 , Yanfang Zhao 1 , Huijuan Li 1 , Mei Zhao 1 , Xiangfeng Chen 1 , Zongwei Cai 2 , Kezhong Fang 3 , Hexing Song 4
Affiliation  

A thorough understanding of the content and distribution of active ingredients in pharmaceuticals is essential for drug efficacy and safety. Technological advancements in mass spectrometry imaging present an opportunity for methodological innovation by providing qualification and quantification analysis, as well as spatial information, in the same assay, which has great potential for applications in the rapid analysis and quality control of drugs.

中文翻译:

基于基质辅助激光解吸/电离质谱成像的土霉素土霉素原位分析

对药物中活性成分的含量和分布的透彻了解对于药物功效和安全性至关重要。质谱成像技术的进步通过在同一分析中提供鉴定和定量分析以及空间信息,为方法学创新提供了机会,这在药物的快速分析和质量控制中具有巨大的潜力。
更新日期:2020-01-15
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