Cytotoxic drug preparation in hospital pharmacies is associated with chronic occupational exposure leading to a risk of adverse effects. The objective was to develop and validate a quantification method for the following cytotoxic drugs in environmental wipe samples: cyclophosphamide, ifosfamide, cytarabine, dacarbazine, docetaxel, paclitaxel, doxorubicin, epirubicin, etoposide, 5‐fluorouracil, gemcitabine, irinotecan, methotrexate and pemetrexed.

中文翻译：

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液相色谱串联质谱定量方法对环境样品中14种细胞毒药物的开发和验证

医院药房中的细胞毒性药物制剂与长期职业接触有关，导致产生不良反应的风险。目的是开发和验证环境擦拭样品中以下细胞毒性药物的定量方法：环磷酰胺，异环磷酰胺，阿糖胞苷，达卡巴嗪，多西他赛，紫杉醇，阿霉素，表柔比星，依托泊苷，5-氟尿嘧啶，吉西他滨，伊立替康，甲氨蝶呤和培美曲塞。