当前位置: X-MOL 学术Nat. Commun. › 论文详情
A predator-prey interaction between a marine Pseudoalteromonas sp. and Gram-positive bacteria
Nature Communications ( IF 11.878 ) Pub Date : 2020-01-15 , DOI: 10.1038/s41467-019-14133-x
Bai-Lu Tang; Jie Yang; Xiu-Lan Chen; Peng Wang; Hui-Lin Zhao; Hai-Nan Su; Chun-Yang Li; Yang Yu; Shuai Zhong; Lei Wang; Ian Lidbury; Haitao Ding; Min Wang; Andrew McMinn; Xi-Ying Zhang; Yin Chen; Yu-Zhong Zhang

Predator-prey interactions play important roles in the cycling of marine organic matter. Here we show that a Gram-negative bacterium isolated from marine sediments (Pseudoalteromonas sp. strain CF6-2) can kill Gram-positive bacteria of diverse peptidoglycan (PG) chemotypes by secreting the metalloprotease pseudoalterin. Secretion of the enzyme requires a Type II secretion system. Pseudoalterin binds to the glycan strands of Gram positive bacterial PG and degrades the PG peptide chains, leading to cell death. The released nutrients, including PG-derived D-amino acids, can then be utilized by strain CF6-2 for growth. Pseudoalterin synthesis is induced by PG degradation products such as glycine and glycine-rich oligopeptides. Genes encoding putative pseudoalterin-like proteins are found in many other marine bacteria. This study reveals a new microbial interaction in the ocean.
更新日期:2020-01-15

 

全部期刊列表>>
化学/材料学中国作者研究精选
Springer Nature 2019高下载量文章和章节
《科学报告》最新环境科学研究
ACS材料视界
自然科研论文编辑服务
中南大学国家杰青杨华明
剑桥大学-
中国科学院大学化学科学学院
材料化学和生物传感方向博士后招聘
课题组网站
X-MOL
北京大学分子工程苏南研究院
华东师范大学分子机器及功能材料
中山大学化学工程与技术学院
试剂库存
天合科研
down
wechat
bug