当前位置: X-MOL 学术Appl. Microbiol. Biotechnol. › 论文详情
Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)
Fungal P450 monooxygenases - the diversity in catalysis and their promising roles in biocontrol activity.
Applied Microbiology and Biotechnology ( IF 5 ) Pub Date : 2019-12-19 , DOI: 10.1007/s00253-019-10305-3
Razak Hussain 1 , Mushtaq Ahmed 2 , Tabreiz Ahmad Khan 1 , Yusuf Akhter 3
Affiliation  

The fungal P450s catalyze vital monooxygenation reactions in primary and secondary metabolism, which may lead to the production of diverse secondary metabolites. Many of these, such as from the family of trichothecenes, involve in biocontrol activities. The diversified nature of fungal P450 monooxygenases makes their host organisms adoptable to various ecological niches. The available genome data analysis provided an insight into the activity and mechanisms of the fungal P450s. However, still more structural and functional studies are needed to elucidate the details of its catalytic mechanism, and the advance studies are also required to decipher further about their dynamic role in various aspects of trichothecene oxygenations. This mini review will provide updated information on different fungal P450 monooxygenases, their genetic diversity, and their role in catalyzing various biochemical reactions leading to the production of plant growth promoting secondary metabolites.

中文翻译:

真菌P450单加氧酶-催化的多样性及其在生物防治活动中的有希望的作用。

真菌P450在初级和次级代谢中催化重要的单加氧反应,这可能导致产生多种次级代谢产物。其中许多,例如来自毛癣菌家族的,涉及生物防治活动。真菌P450单加氧酶的多样性使它们的宿主生物可用于各种生态位。可用的基因组数据分析提供了对真菌P450活性和机制的深入了解。然而,仍然需要更多的结构和功能研究来阐明其催化机理的细节,还需要进行进一步的研究以进一步了解它们在单端孢菌素氧化的各个方面的动态作用。这份小型回顾将提供有关不同真菌P450单加氧酶,其遗传多样性,
更新日期:2020-01-15
down
wechat
bug