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Exploring the powerful phytoarsenal of white grape marc against bacteria and parasites causing significant diseases.
Environmental Science and Pollution Research ( IF 5.8 ) Pub Date : 2020-01-14 , DOI: 10.1007/s11356-019-07472-1
José-Luis Rodríguez Rama 1 , Natalia Mallo 2 , Marco Biddau 2 , Francisco Fernandes 3 , Trinidad de Miguel 1 , Lilach Sheiner 2 , Altino Choupina 3 , Marta Lores 4
Affiliation  

Natural extracts containing high polyphenolic concentration possess antibacterial, anti-parasitic and fungicidal activities. The present research characterises two extracts based on white grape marc, a winemaking by-product, describing their physicochemical features and antimicrobial capacities. The main components of these extracts are phenolic acids, flavan-3-ols and their gallates and flavonols and their glycosides. As a result of this complex composition, the extracts showed pronounced bioactivities with potential uses in agricultural, pharmaceutical and cosmetic industries. Polyphenol compounds were extracted by using hydro-organic solvent mixtures from the by-product of Albariño white wines (Galicia, NW Spain) production. The in vitro antimicrobial activity of these extracts was evaluated on Gram-positive and Gram-negative bacteria and Apicomplexan and Oomycota parasites. Microbial species investigated are causing agents of several human and animal diseases, such as foodborne illnesses (Bacillus cereus, Escherichia coli, Salmonella enterica, and Toxoplasma gondii), skin infections and/or mastitis (Staphylococcus aureus and Streptococcus uberis), malaria (Plasmodium falciparum) and plant infections as "chestnut ink" or "root rot" (Phytophthora cinnamomi). Both extracts showed activity against all the tested species, being nontoxic for the host. So, they could be used for the development of biocides to control a wide range of pathogenic agents and contribute to the enhancement of winemaking industry by-products.

中文翻译:

探索强大的白葡萄渣植物抗药性,防止引起重大疾病的细菌和寄生虫。

含有高浓度多酚的天然提取物具有抗菌,抗寄生虫和杀真菌的活性。本研究表征了一种基于白葡萄渣(一种酿酒副产品)的两种提取物,描述了它们的理化特性和抗菌能力。这些提取物的主要成分是酚酸,黄烷-3-醇及其没食子酸酯和黄酮醇及其糖苷。由于这种复杂的组成,提取物表现出明显的生物活性,在农业,制药和化妆品工业中具有潜在用途。使用有机溶剂混合物从阿尔巴里尼奥白葡萄酒(西班牙西北加里西亚)的副产品中提取多酚化合物。评价了这些提取物对革兰氏阳性和革兰氏阴性细菌以及Apicomplexan和卵菌寄生虫的体外抗菌活性。所调查的微生物物种是导致几种人类和动物疾病的诱因,例如食源性疾病(蜡状芽孢杆菌,大肠杆菌,肠炎沙门氏菌和弓形虫),皮肤感染和/或乳腺炎(金黄色葡萄球菌和乳房链球菌),疟疾(恶性疟原虫) )和植物感染,例如“板栗汁”或“根腐病”(Phytophthora cinnamomi)。两种提取物均对所有被测物种均具有活性,对宿主无毒。因此,它们可用于开发杀菌剂,以控制多种致病因子,并有助于提高酿酒行业的副产品。所调查的微生物物种是导致几种人类和动物疾病的诱因,例如食源性疾病(蜡状芽孢杆菌,大肠杆菌,肠炎沙门氏菌和弓形虫),皮肤感染和/或乳腺炎(金黄色葡萄球菌和乳房链球菌),疟疾(恶性疟原虫) )和植物感染,例如“板栗汁”或“根腐病”(Phytophthora cinnamomi)。两种提取物均对所有被测物种均具有活性,对宿主无毒。因此,它们可用于开发杀菌剂,以控制多种致病因子,并有助于提高酿酒行业的副产品。所调查的微生物物种是导致几种人类和动物疾病的诱因,例如食源性疾病(蜡状芽孢杆菌,大肠杆菌,肠炎沙门氏菌和弓形虫),皮肤感染和/或乳腺炎(金黄色葡萄球菌和乳房链球菌),疟疾(恶性疟原虫) )和植物感染,例如“板栗汁”或“根腐病”(Phytophthora cinnamomi)。两种提取物均对所有被测物种均具有活性,对宿主无毒。因此,它们可用于开发杀菌剂,以控制多种致病因子,并有助于提高酿酒行业的副产品。和弓形虫),皮肤感染和/或乳腺炎(金黄色葡萄球菌和乳房链球菌),疟疾(恶性疟原虫)和植物感染,例如“板栗汁”或“根腐病”(Phytophthora cinnamomi)。两种提取物均表现出针对所有被测物种的活性,对宿主无毒。因此,它们可用于开发杀菌剂,以控制多种致病因子,并有助于提高酿酒行业的副产品。和弓形虫),皮肤感染和/或乳腺炎(金黄色葡萄球菌和乳房链球菌),疟疾(恶性疟原虫)和植物感染,例如“板栗汁”或“根腐病”(Phytophthora cinnamomi)。两种提取物均表现出针对所有被测物种的活性,对宿主无毒。因此,它们可用于开发杀菌剂,以控制多种致病因子,并有助于提高酿酒行业的副产品。
更新日期:2020-01-15
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