Microbial diversity in Peruvian mountain areas is poorly know, specially endophytic microorganisms of medicinal native plants from the Cordillera Blanca. So, nine bacterial and six fungal species were isolated from Gentianella weberbaueri and Valeriana pycnantha. According to 16S rDNA analysis, bacterial strains belong to genera Rahnella, Pseudomonas, Serratia, Rouxiella, and Bacillus; while ITS analysis showed that fungi belong to Pyrenochaeta, Scleroconidioma, Cryptococcus, and Plenodomus genera. Rahnella sp. GT24B and P. trivialis VT20B solubilized tricalcium phosphate and produced siderophores at 10 and 24 °C. Five bacteria strains produced indol-3-acetic acid (IAA) at 10 and 24 °C, where Rahnella sp. VT19B showed more production at 10 °C than 24 °C. Rahnella sp. GT24B, Serratia sp. VT28B, and Rahnella sp. GT25B inhibited Fusarium oxysporum growth up to 100, 78 and 74 %, respectively. R. inusitata VT25B and B. licheniformis GT10B showed high cellulolytic and proteolytic activities. On the other hand, only a few fungi moderately inhibited growth of F. oxysporum, and produced siderophores and cellulases. Most of bacteria inoculated on Medicago sativa “alfalfa” and Triticum aestivum “wheat” seeds got better root development, especially Rahnella sp. GT24B, Rouxiella sp.VT24B, Serratia sp. VT28B, and Rahnella sp. VT34B. Finally, this study is the first report of endophytic microorganisms associated to wild medicinal high-mountain Peruvian plants and it show a valuable microbial diversity and its possible role in promoting growth of crops and wild medicinal plants.

秘鲁山区的微生物多样性知之甚少，尤其是来自白色山脉的药用本地植物的内生微生物。因此，从Gentianella weberbaueri和Valeriana pycnantha中分离了9种细菌和6种真菌。根据16S rDNA分析，细菌菌株属于Rahnella，假单胞菌，沙雷氏菌，Rouxiella和芽孢杆菌属。ITS分析表明真菌属于Pyrenochaeta，Sconroconidioma，Cryptococcus和Plenodomus属。Rahnella sp。GT24B和P. trivialisVT20B溶解了磷酸三钙，并在10和24°C下产生了铁载体。五种细菌菌株在10和24°C下产生了吲哚-3-乙酸（IAA），Rahnella sp。VT19B在10°C时显示出比24°C高的产量。Rahnella sp。Serratia sp.GT24B 。VT28B和Rahnella sp。GT25B抑制尖孢镰刀菌的生长分别高达100％，78％和74％。R. inusitata VT25B和地衣芽孢杆菌GT10B显示出高纤维素分解和蛋白水解活性。另一方面，只有少数真菌适度抑制尖孢镰刀菌的生长，并产生铁载体和纤维素酶。大多数细菌接种在紫花苜蓿“苜蓿”和普通小麦“小麦”种子的根系发育较好，尤其是Rahnella sp。GT24B ，Rouxiella sp.VT24B ，沙雷氏菌 VT28B和Rahnella sp。VT34B。最后，这项研究是有关野生药用高山区秘鲁植物的内生微生物的首次报道，它显示出有价值的微生物多样性及其在促进作物和野生药用植物生长中的可能作用。