Population mobility is an intrinsic human condition. People have always moved over space and time, and always will. Yet mobility can be hard to define and measure, and thus it is challenging to understand the effects of mobility on the spread of HIV. In The Lancet HIV, Oliver Ratmann and colleagues combined social and demographic data with phylogenetic data in an innovative way to measure whether migration led to the spread of HIV from high HIV prevalence fishing communities along Lake Victoria to neighbouring inland communities in south-central Uganda. They asked this important question because HIV prevention efforts and treatment interventions are often prioritised to geographical hotspots, with the implicit assumption that these interventions will also have indirect benefits in neighbouring areas due to infections disseminating from the hotspot. They did not find frequent cross-community HIV transmission between Lake Victoria hotspots and nearby inland populations based on 293 source–recipient pairs with support for epidemiological linkage and direction of transmission. They concluded that, in this particular setting, targeted control of HIV in the lakeside hotspots would have a minimal effect on the epidemic elsewhere.

中文翻译：

---

时间，人口流动和艾滋病毒传播。

人口流动是人类固有的条件。人们总是在时空上移动，并且永远都会。然而，流动性可能难以定义和衡量，因此要了解流动性对HIV传播的影响具有挑战性。在柳叶刀艾滋病，Oliver Ratmann及其同事以一种创新的方式将社会和人口数据与系统发育数据相结合，以衡量迁移是否导致HIV从高感染率的高维多利亚捕鱼社区沿维多利亚湖扩散到乌干达中南部的邻近内陆社区。他们之所以问这个重要问题，是因为艾滋病毒的预防和治疗干预措施通常优先于地理热点地区，并且隐含的假设是，由于从热点地区传播的感染，这些干预措施也将在邻近地区产生间接收益。他们没有发现基于293个源-受者对并支持流行病学联系和传播方向的维多利亚湖热点和附近内陆人口之间的跨社区HIV频繁传播。他们得出结论，