Abstract A simple, sensitive and rapid method of nicotine determination using Boron Doped Diamond Electrode (BDDE) and Differential Pulse Voltammetry (DPV) in electronic cigarette liquids was described. To the best of our knowledge, this is the first presentation of voltammetric method for the determination of nicotine in this type of complex samples. In presented conditions, nicotine undergoes irreversible two-electron oxidation controlled by diffusion process. Optimal measurement parameters were achieved using solution of 25% ammonia in 0.1 mol/L ammonium chloride at pH 7.5 as supporting electrolyte. The calibration graph was linear from 0.03–0.40 mg/L of nicotine, the detection limit was 0.01 mg/L with the correlation coefficient of 0.9950. Sample preparation requires only dilution of the liquid. The effective application of the described simply measurement procedure significantly extends the use of the BDD electrode as an electrochemical sensor. It enables the electrochemical detection of nicotine in samples with a complex chemical composition like liquids for e-cigarettes, which is important in the case of a limited and controlled nicotine concentration in these products.

中文翻译：

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使用掺硼金刚石电极 (BDDE) 伏安法测定电子烟液体中的尼古丁

摘要 描述了一种使用掺硼金刚石电极 (BDDE) 和差示脉冲伏安法 (DPV) 测定电子烟液体中尼古丁的简单、灵敏和快速的方法。据我们所知，这是首次采用伏安法测定此类复杂样品中的尼古丁。在现有条件下，尼古丁经历由扩散过程控制的不可逆双电子氧化。使用 25% 氨的 0.1 mol/L 氯化铵溶液（pH 7.5）作为支持电解质实现了最佳测量参数。校准图在 0.03–0.40 mg/L 尼古丁范围内呈线性，检出限为 0.01 mg/L，相关系数为 0.9950。样品制备只需要稀释液体。所描述的简单测量程序的有效应用大大扩展了 BDD 电极作为电化学传感器的使用。它能够对化学成分复杂的样品（如电子烟液体）中的尼古丁进行电化学检测，这在这些产品中尼古丁浓度有限且受控的情况下非常重要。