当前位置: X-MOL 学术JAMA › 论文详情
Recommendations Related to Genetic Testing for Breast Cancer-Reply.
JAMA ( IF 45.540 ) Pub Date : 2020-01-14 , DOI: 10.1001/jama.2019.18222
Alex H Krist,Douglas K Owens,Carol M Mangione

In Reply Dr Pinsky asks for more clarity on the USPSTF’s recent recommendation. The USPSTF found that women with a personal or family history of breast or ovarian cancer, or an ancestry associated with BRCA1/2 mutations, are at increased risk for having a BRCA1/2 mutation.1 For these women, the benefits of risk assessment and potentially counseling and testing outweigh the harms. Determining whether a woman may be a candidate for referral for counseling and possible genetic testing is a multistep process for primary care clinicians. The first step is to identify women with a personal or family history of breast or ovarian cancer or an ancestry associated with BRCA1/2 mutations (eg, Ashkenazi Jewish women). For these women, the next step is to perform a risk assessment using 1 of several brief risk assessment tools. Last, for women found to be at higher risk using these tools, clinicians should refer or provide genetic counseling. This includes more definitive risk assessment, counseling about genetic testing, shared decision-making about whether to be tested, and potentially genetic testing.

更新日期:2020-01-14

 

全部期刊列表>>
施普林格自然
最近合集,配们化学
欢迎访问IOP中国网站
GIANT
自然职场线上招聘会
ACS ES&T Engineering
ACS ES&T Water
屿渡论文,编辑服务
何川
苏昭铭
陈刚
姜涛
李闯创
复旦大学
刘立明
隐藏1h前已浏览文章
课题组网站
新版X-MOL期刊搜索和高级搜索功能介绍
ACS材料视界
天合科研
x-mol收录
上海纽约大学
曾林
天津大学
何振宇
史大永
吉林大学
卓春祥
张昊
刘冬生
试剂库存
down
wechat
bug