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Morbidity Measures Predicting Mortality in Inpatients: A Systematic Review
Journal of the American Medical Directors Association ( IF 7.6 ) Pub Date : 2020-04-01 , DOI: 10.1016/j.jamda.2019.12.001
Cheng Hwee Soh 1 , Syed Wajih Ul Hassan 1 , Julian Sacre 1 , Andrea B Maier 2
Affiliation  

OBJECTIVES Morbidity is an important risk factor for mortality and a variety of morbidity measures have been developed to predict patients' health outcomes. The objective of this systematic review was to compare the capacity of morbidity measures in predicting mortality among inpatients admitted to internal medicine, geriatric, or all hospital wards. DESIGN A systematic literature search was conducted from inception to March 6, 2019 using 4 databases: Medline, Embase, Cochrane, and CINAHL. Articles were included if morbidity measures were used to predict mortality (registration CRD42019126674). SETTING AND PARTICIPANTS Inpatients with a mean or median age ≥65 years. MEASUREMENTS Morbidity measures predicting mortality. RESULTS Of the 12,800 articles retrieved from the databases, a total of 34 articles were included reporting on inpatients admitted to internal medicine, geriatric, or all hospital wards. The Charlson Comorbidity Index (CCI) was reported most frequently and a higher CCI score was associated with greater mortality risk, primarily at longer follow-up periods. Articles comparing morbidity measures revealed that the Geriatric Index of Comorbidity was better predicting mortality risk than the CCI, Cumulative Illness Rating Scale, Index of Coexistent Disease, and disease count. CONCLUSIONS AND IMPLICATIONS Higher morbidity measure scores are better in predicting mortality at longer follow-up period. The Geriatric Index of Comorbidity was best in predicting mortality and should be used more often in clinical practice to assist clinical decision making.

中文翻译:

预测住院患者死亡率的发病率测量:系统评价

目的 发病率是死亡率的重要危险因素,并且已经开发了多种发病率测量方法来预测患者的健康结果。本系统评价的目的是比较发病率测量在预测内科、老年病房或所有医院病房住院患者死亡率方面的能力。设计 从开始到 2019 年 3 月 6 日,使用 4 个数据库进行了系统的文献检索:Medline、Embase、Cochrane 和 CINAHL。如果使用发病率测量来预测死亡率,则包括文章(注册 CRD42019126674)。地点和参与者 平均或中位年龄≥65 岁的住院患者。测量 发病率测量预测死亡率。结果 在从数据库中检索到的 12,800 篇文章中,共纳入 34 篇报道内科、老年科或所有医院病房的住院患者。查尔森合并症指数 (CCI) 的报告频率最高,较高的 CCI 评分与较高的死亡风险相关,主要是在较长的随访期内。比较发病率的文章表明,老年合并症指数比 CCI、累积疾病评定量表、共存疾病指数和疾病计数更好地预测死亡风险。结论和意义 较高的发病率测量分数在预测较长随访期的死亡率方面更好。老年合并症指数最能预测死亡率,应在临床实践中更频繁地使用,以协助临床决策。查尔森合并症指数 (CCI) 的报告频率最高,较高的 CCI 评分与较高的死亡风险相关,主要是在较长的随访期内。比较发病率的文章表明,老年合并症指数比 CCI、累积疾病评定量表、共存疾病指数和疾病计数更好地预测死亡风险。结论和意义 较高的发病率测量分数在预测较长随访期的死亡率方面更好。老年合并症指数最能预测死亡率,应在临床实践中更频繁地使用,以协助临床决策。查尔森合并症指数 (CCI) 的报告频率最高,较高的 CCI 评分与较高的死亡风险相关,主要是在较长的随访期内。比较发病率的文章表明,老年合并症指数比 CCI、累积疾病评定量表、共存疾病指数和疾病计数更好地预测死亡风险。结论和意义 较高的发病率测量分数在预测较长随访期的死亡率方面更好。老年合并症指数最能预测死亡率,应在临床实践中更频繁地使用,以协助临床决策。比较发病率的文章表明,老年合并症指数比 CCI、累积疾病评定量表、共存疾病指数和疾病计数更好地预测死亡风险。结论和意义 较高的发病率测量分数在预测较长随访期的死亡率方面更好。老年合并症指数最能预测死亡率,应在临床实践中更频繁地使用,以协助临床决策。比较发病率的文章表明,老年合并症指数比 CCI、累积疾病评定量表、共存疾病指数和疾病计数更好地预测死亡风险。结论和意义 较高的发病率测量分数在预测较长随访期的死亡率方面更好。老年合并症指数最能预测死亡率,应在临床实践中更频繁地使用,以协助临床决策。
更新日期:2020-04-01
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