Having a child with cancer may affect the socioeconomic situation of the parents. We aimed to assess the impact of childhood cancer on parental working status and income and to identify determinants of adverse changes after the child's cancer diagnosis by calendar period. We conducted a nationwide cohort study using Danish registry data. Parents of children diagnosed with cancer in 1982–2014 (n = 12,418) were matched with comparison parents of cancer‐free children (n = 125,014). We analysed annual working status (working/not working) and annual disposable income (lowest quintile/not lowest quintile) of case and comparison parents over a period of 10 years after diagnosis by calendar period (1982–1999 vs . 2000–2014). Logistic regression models were used to identify determinants of adverse changes after diagnosis. Mothers of children diagnosed in 1982–1999 were more likely not working or having a low income than comparison mothers up to 10 years after diagnosis. This risk of not working or low income was lower in mothers of children diagnosed in 2000–2014 compared to 1982–1999 in the first years after diagnosis (p _interaction < 0.05). We observed no consistent patterns among fathers. Low parental education, diagnosis of lymphoid leukaemia and younger age of the child at diagnosis were the main determinants of adverse changes in working status or income after diagnosis. Childhood cancer adversely interfered with parents' socioeconomic situation in the earlier calendar period, particularly among mothers. The absence of such an effect in more recent years emphasises the supportive role of a countries’ welfare system alongside the general advances in childhood cancer treatment.

中文翻译：

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丹麦儿童期癌症对父母的工作状态和收入的影响：随着时间的变化和不利变化的决定因素。

生孩子患有癌症可能会影响父母的社会经济状况。我们旨在评估儿童癌症对父母工作状态和收入的影响，并确定在日历期对儿童进行癌症诊断后不良变化的决定因素。我们使用丹麦注册数据进行了全国范围的队列研究。孩子的父母在1982年至2014年（诊断患有癌症ñ = 12418）与无癌名儿童（父母比较相匹配ñ = 125014）。我们分析了日历年（1982年至1999年与诊断后）在10年内父母和病例父母的年度工作状态（工作/不工作）和年度可支配收入（最低五分位数/非最低五分位数）。2000–2014）。Logistic回归模型用于确定诊断后不良变化的决定因素。与直到诊断后十年的比较母亲相比，在1982年至1999年被诊断为儿童的母亲更有可能没有工作或收入较低。在诊断后的头几年，2000-2014年诊断出的儿童母亲的这种不工作或低收入风险要低于1982-1999年（p_相互作用 <0.05）。我们发现父亲之间没有一致的模式。父母教育程度低，诊断为淋巴白血病以及诊断时儿童年龄低是诊断后工作状态或收入不利变化的主要决定因素。在较早的日历时期，儿童癌症不利地影响了父母的社会经济状况，尤其是在母亲当中。近年来没有这种效应强调了一个国家的福利体系在儿童癌症治疗的总体进步中所起的支持作用。