A new simple Schiff base, (E)-N'-(2-hydroxybenzylidene)imidazo[2,1-b]thiazole-6-carbohydrazide (X), was designed and synthesized based on salicylaldehyde and imidazo[2, 1-b]thiazole. X could be used as a sensor to identify Al³⁺ through a significant fluorescence enhancement because of CHEF and inhibition of PET process and then to detect Cu²⁺ through a highly efficient quenching behavior due to the paramagnetic quenching. The sensor showed a high selectivity for Al³⁺ and Cu²⁺ in methanol solution at pH = 5 and was not disturbed by other competing metal ions. Furthermore, based on the equation 3σ/slope, the detection limits of sensor for Al³⁺ and Cu²⁺ were calculated to be 3.1 × 10⁻¹⁰ M and 9.8 × 10^-11 M, respectively. Additionally, the association constants of X[Al³⁺] and X[Cu²⁺] were also determined to be 2.3 × 10⁴ M^-1 and 6.1 × 10⁴ M^-1 on basis of Benesi-Hildebrand equation. In addition, the titration experiment of fluorescence and mass spectrometry showed that sensor was combined with Al³⁺ or Cu²⁺ both in 1:1 ratio. Moreover, the optimized structure and energy calculations of X, X[Al³⁺] and X[Cu²⁺] were obtained by Gaussian software based on the basis set of B3LYP/6−31 G(d) and B3LYP/LANL2DZ. And, the sensor successfully detected Al³⁺ and Cu²⁺ in the real water sample with a satisfactory recovery (91.4 % - 107.1 %) and RSD values (0.66 % - 1.91 %).

一种新的简单的席夫碱，（E）-N' - （2-羟基亚苄基）咪唑并[2,1-b]噻唑-6-碳酰肼（X），设计并合成基于水杨醛和咪唑并[2,1- b噻唑。X可以用作传感器，通过CHEF和抑制PET过程，通过显着的荧光增强来识别Al ³⁺，然后通过顺磁淬灭通过高效淬灭行为检测Cu ²⁺。该传感器对pH = 5的甲醇溶液中的Al ³⁺和Cu ²⁺具有很高的选择性，并且不受其他竞争性金属离子的干扰。此外，基于等式3σ/斜率，传感器对Al ³⁺的检测极限Cu ²⁺和Cu ²⁺分别被计算为3.1×10 ^-10 M和9.8×10 ^-11M。另外，还根据贝内西-希尔德布兰德方程，将X [Al ³⁺ ]和X [Cu ²⁺ ]的缔合常数确定为2.3×10 ⁴ M ^-1和6.1×10 ⁴ M ^-1。此外，荧光和质谱滴定实验表明，传感器与Al ³⁺或Cu ²⁺均以1：1的比例结合。此外，X，X [Al通过高斯软件基于B3LYP / 6-31 G（d）和B3LYP / LANL2DZ的基集获得³⁺ ]和X [Cu ²⁺ ]。并且，该传感器成功检测了真实水样中的Al ³⁺和Cu ²⁺，回收率令人满意（91.4％-107.1％），RSD值（0.66％-1.91％）。