In the present paper, the three-dimensional structure and macroscopic mechanical response of electrospun poly(L-lactide) membranes is predicted based only on the geometry and elasto-plastic mechanical properties of single fibres supplemented by measurements of membrane weight and volume, and the resulting computational models are used to study the non-affine micro-kinematics of electrospun networks. To this end, statistical parameters describing the in-plane fibre morphology are extracted from scanning electron micrographs of the membranes, and computational network models are generated by matching the porosity of the real mats. The virtual networks are compared against computed tomography scans in terms of structure, and against uniaxial tension tests with respect to their macroscopic mechanical response. The obtained virtual network structure agrees well with the fibre disposition in real networks, and the rigorous prediction of the mechanical response of two membranes with mean diameters of 1.10$\mathrm{\mu }$m and 0.70$\mathrm{\mu }$m captures the experimental behaviour qualitatively. Favourable quantitative agreement, however, is obtained only after lowering the Young's moduli, yield stresses and hardening slopes determined in single fibre tests, and after reducing the density of inter-fibre bonds in the model of the membrane with thinner fibres. The simulations thus demonstrate the validity and merits of the approach to study the multi-scale mechanics of electrospun networks, but also point to potential discrepancies between the properties of electrospun fibres within a network and those produced for single fibre characterisation, and highlight the existing uncertainty on the density and quality of bonds between fibres in electrospun networks.

在本文中，仅基于单纤维的几何形状和弹塑性力学性能，并辅以膜重量和体积的测量，来预测电纺聚（L-丙交酯）膜的三维结构和宏观力学响应。所得的计算模型用于研究电纺网络的非仿射微运动学。为此，从膜的扫描电子显微照片中提取描述面内纤维形态的统计参数，并通过匹配实际毡的孔隙率来生成计算网络模型。将虚拟网络在结构上与计算机断层扫描进行比较，并就其宏观机械响应与单轴拉伸测试进行比较。$\mathrm{\mu }$m和0.70$\mathrm{\mu }$m定性捕获实验行为。但是，只有在降低单纤维测试中确定的杨氏模量，屈服应力和硬化斜率之后，并在使用较细纤维的膜模型中降低纤维间键合的密度之后，才能获得良好的定量一致性。因此，仿真证明了研究电纺网络多尺度力学方法的有效性和优点，但也指出了网络内电纺纤维的性能与为单纤维表征而产生的性能之间的潜在差异，并突出了现有的不确定性静电纺丝网络中纤维间键合的密度和质量