BACKGROUND The aim of this study was to investigate the concordance between ventilator-associated events (VAE) and ventilator-associated lower respiratory tract infections (VA-LRTI), and their impact on outcome. METHODS This retrospective study was performed in five 10-bed ICUs of a teaching hospital, during a 2-year period. Ventilator-associated lower respiratory tract infections (VA-LRTI), including ventilator-associated tracheobronchitis (VAT) and ventilator-associated pneumonia (VAP) were prospectively diagnosed. The agreement between VAE, VAT and VAP was assessed by k statistics. RESULTS A total of 1059 patients (15,029 ventilator-days) were included. 268 VAP (17.8 per 1000 ventilator-days), 127 VAT (8.5 per 1000 ventilator-days) and 262 VAE (17.4 per 1000 ventilator-days) were diagnosed. There was no agreement between VAT and VAE, and the agreement was poor between VAP and VAE (k = 0.12, 95% CI 0.03-0.20). VAE and VA-LRTI were associated with significantly longer duration of mechanical ventilation, ICU and hospital length of stay. VAP, VAT and VAE were not significantly associated with mortality in multivariate analysis. CONCLUSIONS The agreement was poor between VAE and VAP. No agreement was found between VAE and VAT. VAE episodes were significantly associated with longer duration of mechanical ventilation and length of stay, but not with ICU mortality.

中文翻译：

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呼吸机相关事件在诊断呼吸机相关下呼吸道感染中的准确性。

背景技术这项研究的目的是研究呼吸机相关事件（VAE）与呼吸机相关下呼吸道感染（VA-LRTI）之间的一致性，以及它们对预后的影响。方法这项回顾性研究在2年的时间里，在教学医院的5个10张病床的ICU中进行。前瞻性诊断呼吸机相关的下呼吸道感染（VA-LRTI），包括呼吸机相关的气管支气管炎（VAT）和呼吸机相关的肺炎（VAP）。VAE，VAT和VAP之间的协议由k统计量评估。结果总共包括1059例患者（呼吸机天数为15029天）。诊断出268 VAP（每1000呼吸机天数17.8），127增值税（每1000呼吸机天数8.5）和262 VAE（每1000呼吸机天数17.4）。增值税和VAE之间没有协议，并且VAP和VAE之间的一致性差（k = 0.12，95％CI 0.03-0.20）。VAE和VA-LRTI与机械通气时间，ICU和住院时间长得多有关。在多变量分析中，VAP，VAT和VAE与死亡率没有显着相关。结论VAE和VAP之间的协议不佳。VAE和VAT之间未找到协议。VAE发作与较长时间的机械通气和住院时间显着相关，但与ICU死亡率无关。结论VAE和VAP之间的协议不佳。VAE和VAT之间未找到协议。VAE发作与较长时间的机械通气和住院时间显着相关，但与ICU死亡率无关。结论VAE和VAP之间的协议不佳。VAE和VAT之间未找到协议。VAE发作与较长时间的机械通气和住院时间显着相关，但与ICU死亡率无关。