In common with all segmented negative-sense RNA viruses, bunyavirus transcripts contain heterologous sequences at their 5' termini originating from capped host cell RNAs. These heterologous sequences are acquired by a so-called cap-snatching mechanism. Whereas for nuclear replicating influenza virus the source of capped primers as well as the cap-binding and endonuclease activities of the viral polymerase needed for cap snatching have been functionally and structurally well characterized, our knowledge on the expected counterparts of cytoplasmic replicating bunyaviruses is still limited and controversial. This review focuses on the cap-snatching mechanism of bunyaviruses in the light of recent structural and functional data.

中文翻译：

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Bunyaviruses的抢帽机制。

与所有分段的负义RNA病毒一样，布尼亚病毒转录本在其5'末端包含源自有帽宿主细胞RNA的异源序列。这些异源序列是通过所谓的帽捕获机制获得的。尽管对于核复制型流感病毒而言，在功能和结构上已经很好地表征了帽捕获的加帽引物的来源以及病毒聚合酶的帽结合和核酸内切酶活性，但是我们对胞质复制布尼亚病毒的预期对应物的了解仍然有限和有争议的。鉴于最近的结构和功能数据，这篇综述着重于布尼亚病毒的抢帽机制。