We herein used Ag2Se quantum dots (QDs) as a target-modulated sensitizer for upconversion nanoparticles (UCNPs) and the target thrombin as the sensitizing switch to construct a biosensor, circumventing the limited luminescence resonance energy transfer (LRET) efficiency of UCNPs, with enhanced signal-to-background ratio (SBR) and assay sensitivity.

中文翻译：

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NIR发射量子点对上转换发光的靶标调制敏化：构建上转换生物传感器的新策略。

我们在本文中使用Ag2Se量子点（QDs）作为上转换纳米粒子（UCNPs）的目标调节敏化剂，并使用目标凝血酶作为敏化开关来构建生物传感器，从而规避了UCNPs有限的发光共振能量转移（LRET）效率，并且信噪比（SBR）和测定灵敏度。