CLU rs11136000 promotes early cognitive decline in Parkinson's disease,Movement Disorders

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CLU rs11136000 promotes early cognitive decline in Parkinson's disease
Movement Disorders ( IF 8.6 ) Pub Date : 2020-01-13 , DOI: 10.1002/mds.27949
Frederic Sampedro _{1,

2,

3} , Juan Marín-Lahoz _{1,

2,

3} , Saul Martínez-Horta _{1,

2,

3} , Rocío Pérez-González _{1,

2,

3} , Javier Pagonabarraga _{1,

2,

3} , Jaime Kulisevsky _{1,

2,

3}

Affiliation

The C allele of the rs11136000 genetic variant of the clusterin gene has been associated with increased risk of Alzheimer's disease. However, a comprehensive characterization of the role of this genetic variant in early cognitive deterioration in PD is lacking.

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