TXNIP hypomethylation and its interaction with obesity and hypertriglyceridemia increase type 2 diabetes mellitus risk: A nested case-control study.,Journal of Diabetes

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TXNIP hypomethylation and its interaction with obesity and hypertriglyceridemia increase type 2 diabetes mellitus risk: A nested case-control study.
Journal of Diabetes ( IF 4.5 ) Pub Date : 2020-01-23 , DOI: 10.1111/1753-0407.13021
Dongdong Zhang _{1,

2} , Cheng Cheng _{1,

2} , Meng Cao ₃ , Tieqiang Wang ₄ , Xiaoliang Chen ₄ , Yang Zhao _{1,

2,

5} , Bingyuan Wang _{1,

2,

5} , Yongcheng Ren _{1,

2,

4} , Dechen Liu _{1,

2,

4} , Leilei Liu _{1,

2} , Xu Chen ₁ , Feiyan Liu ₁ , Qionggui Zhou ₁ , Gang Tian ₄ , Quanman Li ₄ , Chunmei Guo ₄ , Honghui Li ₁ , Jian Wang ₁ , Ruirong Cheng ₁ , Dongsheng Hu _{1,

2,

5} , Ming Zhang _{1,

2}

Affiliation

This study aims to estimate type 2 diabetes mellitus (T2DM) incidence with DNA methylation of the thioredoxin‐interacting protein (TXNIP) gene and its interaction with environmental factors.

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